The PROGINS polymorphism of the human progesterone receptor diminishes the response to progesterone
نویسندگان
چکیده
منابع مشابه
The progins progesterone receptor gene polymorphism is not related to endometriosis‐associated infertility or to idiopathic infertility
OBJECTIVE This study aimed to determine the frequency of the PROGINS polymorphism in women with endometriosis-associated infertility, in infertile women without endometriosis and in controls. INTRODUCTION The human progesterone receptor gene has two isoforms that modulate the biological action of progesterone: isoform A, which is capable of inhibiting the activation of the estrogen receptors,...
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15 صفحه اولThe progesterone receptor PROGINS polymorphism is not related to oxidative stress factors in women with polycystic ovary syndrome
BACKGROUND Women with PCOS have been reported to be at increased risk of a number of gynaecological neoplasias, including endometrial, breast, and ovarian cancer. Studies of the possible association of genetic variation in progesterone receptor polymorphism with risk of ovarian and breast cancer have concentrated on a variant known as PROGINS. METHODS Ninety-five young women with PCOS and 99 ...
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ژورنال
عنوان ژورنال: Journal of Molecular Endocrinology
سال: 2007
ISSN: 0952-5041,1479-6813
DOI: 10.1677/jme.1.02170